Association between poor tolerability of antidepressant treatment and brain functional activation in youth at risk for bipolar disorder.

Fabiano G NerySheela L MasifiJeffrey R StrawnLuis R DuranWade A WeberJeffrey A WelgeCaleb M AdlerStephen M StrakowskiMelissa P DelBello

Published in: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) (2021)

Decreased right amygdala activation in response to emotional distracters is associated with experiencing an antidepressant-related adverse reaction in at-risk youth. Further studies to determine whether amygdala activation is a useful biomarker for antidepressant-related adverse events are needed.

Keyphrases

major depressive disorder
bipolar disorder
resting state
functional connectivity
mental health
physical activity
emergency department
multiple sclerosis
randomized controlled trial
prefrontal cortex
clinical trial
drug induced