Neuroimmune expression in hip osteoarthritis: a systematic review.

Manuel Ribeiro da SilvaDaniela LinharesDaniel Marques VasconcelosCecilia Juliana AlvesNuno NevesGilberto CostaMeriem Lamghari

Published in: BMC musculoskeletal disorders (2017)

For the first time a systematic review on neuroimmune expression in patients with hip OA found an upregulation of neuroimmune markers, with deregulated balance between pro and anti-inflammatory cytokines. However, no clear systematic pattern was found, and few information is available on nervous expression. This highlights the importance of future research with clear methodologies to guide the management of these patients.

Keyphrases

poor prognosis
long non coding rna
end stage renal disease
binding protein
knee osteoarthritis
cell proliferation
signaling pathway
healthcare
total hip arthroplasty
health information
patient reported outcomes