Celecoxib and Afatinib synergistic enhance radiotherapy sensitivity on human non-small cell lung cancer A549 cells.
Pan ZhangErqun SongMingdong JiangYang SongPublished in: International journal of radiation biology (2020)
Our results suggested that Celecoxib and Afatinib regulate cell sensitivity to apoptosis, and thus modulate the resistance of NSCLC to radiation.
Keyphrases
- cell cycle arrest
- advanced non small cell lung cancer
- induced apoptosis
- cell death
- endoplasmic reticulum stress
- endothelial cells
- epidermal growth factor receptor
- small cell lung cancer
- pi k akt
- oxidative stress
- early stage
- radiation induced
- single cell
- cell therapy
- induced pluripotent stem cells
- locally advanced
- pluripotent stem cells
- stem cells
- squamous cell carcinoma