Individual factors including age, BMI and heritable factors underlie temperature variation in sickness and in health: an observational, multi-cohort study.

Rose S PenfoldMaria Beatrice ZazzaraMarc F Österdahlnull nullCarly WelchMary Ni LochlainnMaxim B FreidinRuth C E BowyerEllen ThompsonMichela AntonelliYu Xian Rachel TanCarole H SudreMarc ModatBenjamin MurrayJonathan WolfSebastien OurselinTonny VeenithJanet M LordClaire J Steves

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)

Ageing affects temperature in health and acute infection, with significant heritability, indicating genetic factors contribute to temperature regulation. Our observations suggest a lower threshold (37.4°C/97.3°F) for identifying fever in older adults ≥65 years.

Keyphrases

healthcare
public health
mental health
liver failure
physical activity
health information
body mass index
gene expression
intensive care unit
genome wide
cross sectional
risk assessment
drug induced
dna methylation
copy number