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A rare case of hepatoid gastric adenocarcinoma.

Elena Pablo-MartínLaura Corvo-FélixJonnathan Roldán RuizJuan Carlos Redondo GonzálezLourdes Cuesta MartínezPablo Reguera PuertasLuis Figuero PérezEmilio Fonseca-Sánchez
Published in: Revista espanola de enfermedades digestivas (2024)
Hepatoid gastric adenocarcinoma (HGA) is a rare subtype of gastric cancer. It usually presents with non-specific digestive tract symptoms and is usually diagnosed in advanced stages. It has radiological and histological similarities to hepatocarcinoma (HCC), and serum elevation of alpha-fetoprotein (AFP) is characteristic, as is positive staining for this marker on immunohistochemistry. Given the low incidence and poor prognosis of this type of tumour, it is essential to make a correct differential diagnosis and to initiate early surgical treatment in localised stages and systemic treatment in those where the disease is disseminated. In this context, we present the case of a GHA diagnosed this year in our centre.
Keyphrases
  • poor prognosis
  • rare case
  • long non coding rna
  • squamous cell carcinoma
  • locally advanced
  • risk factors
  • physical activity
  • rectal cancer
  • flow cytometry
  • depressive symptoms
  • replacement therapy