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Polar lipids modify Alzheimer's Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation.

Sakshi HansJanelle E StantonAnn Katrin SauerKatie ShielsSushanta Kumar SahaRonan LordanAlexandros B TsouprasIoannis ZabetakisAndreas Martin Grabrucker
Published in: Lipids in health and disease (2024)
Our results highlight a novel underlying mechanism, why consuming PL-rich foods such as fish and dairy may reduce the risk of developing dementia and associated disorders.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • signaling pathway
  • cognitive impairment
  • fatty acid