Cytokines and Cortisol - predictors of treatment response to corticosteroids in community-acquired pneumonia?

Sandrine Andrea UrwylerC A BlumM CoslovskyB MuellerP SchuetzM Christ-Crain

Published in: Journal of internal medicine (2019)

The imbalance of high inflammation state and low cortisol levels did not predict treatment response to corticosteroids in patients with CAP. However, in line to previous research, inflammation as measured by cytokine levels irrespective of cortisol tended to predict treatment response to corticosteroids in CAP. Whether this concept may help to personalize corticosteroids to patients most likely benefitting from this treatment needs to be tested in future intervention trials.

Keyphrases

community acquired pneumonia
end stage renal disease
randomized controlled trial
ejection fraction
newly diagnosed
peritoneal dialysis
current status
patient reported