Expression of Neurotensin and its Receptors Along the Intestinal Tract in Type 2 Diabetes Patients and Healthy Controls.
Hannah Gilliam-VighTina JorsalSophie W NielsenJulie L FormanJens PedersenSteen Seier PoulsenTina VilsbøllFilip K Krag KnopPublished in: The Journal of clinical endocrinology and metabolism (2023)
This unique intestinal mapping of N cell density and NTS expression shows increasing levels from the small intestine's proximal to distal end (without differences between patients with type 2 diabetes and healthy controls), while negligible N cells and NTS mRNA expression were observed in the large intestine. Sortilin was expressed throughout the intestines in both groups; no NTS receptor 1 or 2 mRNA expression were detected.
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