High tissue expression of TLRs combined with high density of tumor infiltrating lymphocytes predicts a better prognosis in colorectal cancer patients.

Ines Beilmann-LehtonenJussi KasurinenJaana HagströmTuomas KaprioCamilla BöckelmanCaj Haglund

Published in: PloS one (2023)

We detected significant associations and correlations between high tissue TLR2, TLR4, and TLR5 immunoexpressions and high densities of CD3- and CD8-positive cells. Combining these markers may improve the prognostic evaluation of CRC patients.

Keyphrases

toll like receptor
high density
inflammatory response
immune response
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
poor prognosis
peritoneal dialysis
cell proliferation
patient reported outcomes
binding protein
endoplasmic reticulum stress