Clonality, virulence determinants, and profiles of resistance of clinical Acinetobacter baumannii isolates obtained from a Spanish hospital.
Elias DahdouhRosa Gómez-GilSonsoles PachoJesús MingoranceZiad DaoudMonica SuárezPublished in: PloS one (2017)
An alarmingly high rate of carbapenem non-susceptibility has been detected in this study. There was a predominance of IC II and blaOXA-24-like, and those factors were associated with heightened expression of virulence determinants. This association could be exploited for modifying treatment regimens and for improving on infection control protocols in this hospital.
Keyphrases
- acinetobacter baumannii
- pseudomonas aeruginosa
- multidrug resistant
- drug resistant
- biofilm formation
- cystic fibrosis
- escherichia coli
- staphylococcus aureus
- healthcare
- poor prognosis
- antimicrobial resistance
- acute care
- adverse drug
- klebsiella pneumoniae
- gram negative
- emergency department
- binding protein
- combination therapy
- smoking cessation