Login / Signup

Vestibular prepulse inhibition of the human blink reflex.

Matteo CioccaSarah HosliZaeem HadiMohammad MahmudYen F TaiBarry M Seemungal
Published in: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology (2024)
The main brainstem nucleus mediating PPI - the pedunculopontine nucleus (PPN) - is heavily vestibular responsive, which is consistent with our findings of a vestibular-mediated PPI. Our technique may be used to interrogate the fidelity of brain circuits mediating vestibular-related PPN functions. Given the PPN's importance in human postural control, our technique may also provide a neurophysiological biomarker of balance.
Keyphrases
  • endothelial cells
  • hearing loss
  • induced pluripotent stem cells
  • pluripotent stem cells
  • white matter
  • drug delivery
  • small molecule
  • cerebral ischemia
  • subarachnoid hemorrhage