The Effect of Antihypertensive Drugs on NADH in Newly Diagnosed Primary Hypertension.
Regina Pawlak-ChomickaTomasz KrauzePaweł UruskiJaroslaw PiskorskiAndrzej WykrętowiczAndrzej TykarskiPrzemyslaw GuzikPublished in: Cardiology research and practice (2022)
Amlodipine, perindopril, and nebivolol appear neutral for the skin NADH content during the 6-week antihypertensive treatment. Similar treatment with metoprolol increased skin NADH at rest, during ischemia and reperfusion, probably due to an effect on microcirculation and altered mitochondrial function. Explanation of the potential mechanisms behind metoprolol influence on the skin NADH metabolism requires further investigation.
Keyphrases
- blood pressure
- hypertensive patients
- newly diagnosed
- soft tissue
- wound healing
- acute myocardial infarction
- randomized controlled trial
- heart failure
- acute coronary syndrome
- risk assessment
- acute ischemic stroke
- left ventricular
- climate change
- atrial fibrillation
- subarachnoid hemorrhage
- study protocol
- arterial hypertension