Unbalanced human embryos secrete more hyperglycosylated human chorionic gonadotrophin (hCG-H) than balanced ones.
Dimitar Angelov ParvanovDragomira NikolovaRumiana GanevaKristina NikolovaMagdalena VasilevaIvaylo RangelovMaria PanchevaMaria SerafimovaRada StanevaSavina HadjidekovaFabio ScarpelliniGeorgi StamenovPublished in: Journal of assisted reproduction and genetics (2020)
Our results suggest that chromosomal aberrations in human embryos are associated with an increased secretion of hCG-H. However, hCG-H concentration in embryo culture media as a single biomarker is not sufficient for an accurate selection of balanced embryos.