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Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [64Cu]Cu-NOTA-anti-CD8 PET.

Veronica L NagleKelly E HenryCharli Ann J HertzMaya Srikanth GrahamCarl CamposLuis F ParadaNeeta Pandit-TaskarAndrea SchietingerIngo K MellinghoffJason S Lewis
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Human CD8+ T cells infiltrate an orthotopic GBM in a donor-dependent manner. Furthermore, [64Cu]Cu-NOTA-anti-CD8 quantitatively images both peripheral and brain parenchymal human CD8+ T cells.
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