Human Epidermal Growth Factor Receptor 2 Status in Gastric Carcinomas with Distinctive Prevalent Cribriform Component.
Antonio IeniGiuseppe AngelicoValeria BarresiGiuseppe GiuffrèFrancesco ArenaRosario Alberto CarusoGiovanni TuccariPublished in: Disease markers (2018)
Our data confirmed a worse prognosis in all CGC patients with HER2 amplification, resulting in a shorter survival time. We invite all pathologists in their daily practice to specify the occurrence of cribriform neoplastic component in GC, either in surgical or in bioptical samples, taking into practical assessment the high HER2 overexpression rate in order to correctly treat these patients with worse behavior.
Keyphrases
- epidermal growth factor receptor
- tyrosine kinase
- advanced non small cell lung cancer
- endothelial cells
- primary care
- healthcare
- risk assessment
- induced pluripotent stem cells
- cell proliferation
- high grade
- transcription factor
- physical activity
- pluripotent stem cells
- free survival
- machine learning
- simultaneous determination