Long-term experience with biohybrid cochlear implants in human neurosensory restoration.
Dragana Mitovska FenovRolf SalcherEugen KludtAnke Lesinski-SchiedatJennifer HarreThomas LenarzAnja GiesemannAthanasia WarneckePublished in: Cochlear implants international (2024)
Due to satisfactory outcomes and lack of complications, the biohybrid electrode is considered to be a safe option in cochlear implantation. The simplicity of application of autologous cells as a source of anti-inflammatory and neuroprotective factors via a biohybrid electrode array is a key step for cell-based, regenerative therapies for deafness.
Keyphrases
- cell therapy
- anti inflammatory
- induced apoptosis
- stem cells
- endothelial cells
- mesenchymal stem cells
- single cell
- cell cycle arrest
- carbon nanotubes
- high throughput
- induced pluripotent stem cells
- bone marrow
- risk factors
- high resolution
- pluripotent stem cells
- endoplasmic reticulum stress
- type diabetes
- cell proliferation
- cell death
- soft tissue
- metabolic syndrome
- insulin resistance
- platelet rich plasma
- oxidative stress
- adipose tissue
- skeletal muscle
- blood brain barrier