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Dynamic contrast-enhanced computed tomography for the diagnosis of solitary pulmonary nodules: a systematic review and meta-analysis.

Jonathan Richard Weir-McCallStella JoyceAndrew CleggJames W MacKayGabrielle BaxterLena-Marie DendlRobert C RintoulNagmi R QureshiKen MilesFiona J Gilbert
Published in: European radiology (2020)
• The pooled accuracy results were sensitivity 95.1% and specificity 73.8% although individual studies showed wide ranges of values. • This is comparable to the results of previous meta-analyses of PET/CT (positron emission tomography/computed tomography) diagnostic accuracy for the diagnosis of solitary pulmonary nodules. • Robust direct comparative accuracy and cost-effectiveness studies are warranted to determine the optimal use of DCE-CT and PET/CT in the diagnosis of SPNs.
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