Long non‑coding RNA LINC00460 contributes as a potential prognostic biomarker through its oncogenic role with ANXA2 in colorectal polyps.

Farzaneh Alsadat HosseiniLeili RejaliMohammad Reza ZabihiZahra SalehiElahe Daskar-AbkenarTannaz TarazNayeralsadat FatemiMehrdad HashemiHamid Asadzadeh-AghdaeiEhsan Nazemalhosseini Mojarad

Published in: Molecular biology reports (2023)

In conclusion, the expression of the ANXA2 and LINC00460 were significantly elevated in pre-cancerous polyps, especially in high-risk adenomas. Collectively, ANXA2 and LINC00460 may be administered as potential prognostic biomarkers in patients with a precancerous large intestine lesion as an alarming issue.

Keyphrases

long non coding rna
poor prognosis
chronic rhinosinusitis
human health
long noncoding rna
binding protein