Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma.

Martin Krkoška Jana NekvindováKateřina NevědělováVeronika ZubáňováLenka RadováJan VondráčekJarmila HerůdkováOndřej SlabýIgor KissLucia BohovicováPavel FabianZuzana TylichováZdeněk KalaPetr KyselaLenka OstřížkováVladimír Palička Alena Hyršlová Vaculová

Published in: Pharmacological reports : PR (2021)

Our results revealed a novel role of miR-653 and miR-29c in regulation of expresion of CYPs involved in crucial biotransformation processes in liver, which are often deregulated during liver cancer progression.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
poor prognosis
single cell
binding protein