Login / Signup

CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation.

Christine M WardellVivian C W FungEleanor ChenManjurul HaqueJana GilliesJustin A SpanierMajid MojibianBrian T FifeMegan K Levings
Published in: bioRxiv : the preprint server for biology (2024)
Alloreactive chimeric antigen receptor-engineered regulatory T cells limit diabetogenic T cell engraftment and function to prevent type 1 diabetes.
Keyphrases
  • regulatory t cells
  • type diabetes
  • dendritic cells
  • glycemic control
  • cardiovascular disease
  • insulin resistance
  • immune response
  • mesenchymal stem cells
  • cord blood