Characterizing the Relationship between Expression Quantitative Trait Loci (eQTLs), DNA Methylation Quantitative Trait Loci (mQTLs), and Breast Cancer Risk Variants.

Peh-Joo Ho Alexis Jiaying Khng Kiat Tee Benita TanChiea Chuen KhorErn Yu TanGeok Hoon LimWoon-Puay KohSu-Ming TanXuling ChangVeronique Kiak Mien TanXueling S Sim Rajkumar Dorajoo Woon Puay Koh Mikael Hartman Jingmei Li

Published in: Cancers (2024)

While this study identified potentially functional variants associated with breast cancer risk, their inclusion did not substantially enhance the predictive accuracy of the GWAS PRS.

Keyphrases

breast cancer risk
genome wide
dna methylation
copy number
genome wide association study
high resolution
poor prognosis
gene expression
mass spectrometry
long non coding rna