Time-efficient combined morphologic and quantitative joint MRI: an in situ study of standardized knee cartilage defects in human cadaveric specimens.
Teresa LemainqueNicola PridöhlShuo ZhangMarc HuppertzManuel PostCan YükselMasami YoneyamaAndreas PrescherChristiane KuhlDaniel TruhnSven NebelungPublished in: European radiology experimental (2024)
• Combined morphologic and quantitative MIXTURE sequences are based on three-dimensional TSE contrasts. • MIXTURE sequences were studied in an in situ human cartilage defect model. • Morphologic image features, i.e., defect delineabilty and bone texture, were investigated. • Morphologic image features were similar between MIXTURE and reference sequences. • MIXTURE allowed time-efficient simultaneous morphologic and quantitative knee joint assessment.
Keyphrases
- endothelial cells
- high resolution
- deep learning
- induced pluripotent stem cells
- pluripotent stem cells
- contrast enhanced
- magnetic resonance imaging
- total knee arthroplasty
- extracellular matrix
- bone mineral density
- knee osteoarthritis
- genetic diversity
- mass spectrometry
- postmenopausal women
- bone loss
- clinical evaluation