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The relative isoform expression levels of isocitrate dehydrogenase in breast cancer: IDH2 is a potential target in MDA-MB-231 cells.

Shuyu PiaoSeonhee KimYoungduk SeoJinsun LeeSunhee JeonGiang-Huong VuMin-Kyung YeoCuk-Seong Kim
Published in: Korean journal of clinical oncology (2023)
These findings suggest that different from IDH1 and IDH3, IDH2 is more highly expressed in stages 2 and 3 breast cancer tissues, especially in triple-negative breast cancer. IDH2 potentially serves as a target to detect unknown mechanisms in breast cancer.
Keyphrases
  • low grade
  • wild type
  • high grade
  • cell cycle arrest
  • poor prognosis
  • gene expression
  • cell death
  • signaling pathway
  • long non coding rna