Probiotic supplementation increases obesity with no detectable effects on liver fat or gut microbiota in obese Hispanic adolescents: a 16-week, randomized, placebo-controlled trial.
Roshonda B JonesT L AldereteA A MartinB A GearyD H HwangS L PalmerM I GoranPublished in: Pediatric obesity (2018)
VSL#3 supplementation may lead to increased adiposity in obese Latino adolescents with no significant detectable changes in gut microbiota, gut appetite-regulating hormones, liver fat and fibrosis and dietary intake. However, it is important to note that recruitment efforts were terminated early and the sample size fell short of what was planned for this trial.
Keyphrases
- weight loss
- adipose tissue
- insulin resistance
- double blind
- young adults
- phase iii
- metabolic syndrome
- placebo controlled
- bariatric surgery
- phase ii
- physical activity
- type diabetes
- study protocol
- clinical trial
- african american
- weight gain
- open label
- obese patients
- high fat diet induced
- fatty acid
- skeletal muscle
- body mass index
- body weight