Primary outcomes and characteristics of clinical trial registries (up to October 2021) on COVID-19 vaccines.
Yuri Yokoyama do NascimentoMatheus Aparecido de ToledoDaniel Maringelli PasquiRafael Leite PachecoRachel RieraPublished in: Journal of evaluation in clinical practice (2024)
the primary outcomes of clinical trials on COVID-19 vaccines are poorly described, and the registers provide insufficient information about them. The registry was retrospectively fulfilled for many trials, which may lead to bias and research waste. Outcomes were generically described and did not provide transparent information for replication in practice, further trials or meta-analyses.