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Technological mapping and trends in photobioreactors for the production of microalgae.

P C S KirnevJulio Cesar de CarvalhoLuciana Porto de Souza VandenbergheS G KarpCarlos Ricardo Soccol
Published in: World journal of microbiology & biotechnology (2020)
Photobioreactors (PBRs) are equipment of central importance for the massive cultivation of microalgae, providing controlled conditions for high cell productivity. There are a few popular PBR designs, with contrasting advantages and limitations, such as poor light distribution, mass transfer, or hydrodynamic behavior. Due to the environmental concerns in recent decades and the discovery of new, useful microalgal metabolites, the interest in finding alternatives to solve technological bottlenecks of PBRs has intensified. In this process, new geometries, materials, and modes of light supply were developed, generating a significant scientific and technological output, reported in papers and patents. We present a technological landscape analysis of photobioreactor design, focusing on improvements of the classical geometries and trends in industrial photobioreactors. The analysis of 412 patent documents showed a surge in innovation filing since 2005 and a reduction in the number of new documents along the last decade. The recent efforts in design improvement, the leading countries, institutes and companies that innovate, and the trends in PBR technology are presented and discussed.
Keyphrases
  • single cell
  • climate change
  • small molecule
  • high resolution
  • stem cells
  • anaerobic digestion
  • risk assessment
  • cell therapy
  • mass spectrometry
  • quality improvement
  • bone marrow