EGFR, HER2, and MET gene amplification and protein expression profiles in biliary tract cancer and their prognostic significance.
Yeseul KimSeungyun JeeHyunsung KimSeung Sam PaikDongho ChoiSu Hyun YooSu-Jin ShinPublished in: The oncologist (2024)
Our data suggested that MET, HER2, and EGFR might be potential therapeutic targets and that their co-expression is a strong prognostic factor for BTCs.
Keyphrases
- tyrosine kinase
- prognostic factors
- epidermal growth factor receptor
- small cell lung cancer
- papillary thyroid
- poor prognosis
- binding protein
- squamous cell
- electronic health record
- copy number
- genome wide
- big data
- nucleic acid
- protein protein
- amino acid
- dna methylation
- childhood cancer
- machine learning
- lymph node metastasis
- gene expression
- human health
- genome wide identification
- squamous cell carcinoma
- long non coding rna
- young adults
- data analysis
- risk assessment
- label free
- genome wide analysis