Role of protein kinase A and A kinase anchoring proteins in buffering and compartmentation of cAMP signalling in human airway smooth muscle cells.

Rinzhin T SherpaKarni S MoshalShailesh R AgarwalRennolds S OstromRobert D Harvey

Published in: British journal of pharmacology (2024)

Our results confirm that AKAP-anchored PKA contributes to the buffering of cAMP and is consequential in the compartmentation of cAMP responses in hASM cells.

Keyphrases

protein kinase
induced apoptosis
endothelial cells
binding protein
cell cycle arrest
induced pluripotent stem cells
endoplasmic reticulum stress
signaling pathway
oxidative stress
pluripotent stem cells
cell death