Anticoagulation Prescribing Patterns in Intensive Care Unit Patients Admitted with Prehospital Direct Oral Anticoagulant Therapy: A Single Academic Center Experience.
Amos LalOsama MukhtarSarah J ChalmersJohn KarpPatrick M WieruszewskiJohn G ParkPublished in: Hospital pharmacy (2022)
Our single-center retrospective study describes the current prescribing practices and preliminary outcomes in ICU patients with prehospital use of DOACs. Up to 20% of the patients were transitioned to a different agent within 24 hours of ICU admission, whereas a significant proportion of patients (42%) had anticoagulation discontinued altogether. Most patients who suffered a major bleeding episode required either endoscopic or surgical intervention to control bleeding.
Keyphrases
- intensive care unit
- atrial fibrillation
- end stage renal disease
- primary care
- newly diagnosed
- ejection fraction
- chronic kidney disease
- cardiac arrest
- randomized controlled trial
- peritoneal dialysis
- prognostic factors
- healthcare
- emergency department
- stem cells
- mechanical ventilation
- type diabetes
- patient reported outcomes
- metabolic syndrome
- adipose tissue
- mesenchymal stem cells
- adverse drug