Autoimmune retinopathy with associated anti-retinal antibodies as a potential immune-related adverse event associated with immunotherapy in patients with advanced cutaneous melanoma: case series and systematic review.
Jacob S HengJenna M KimD Kyle JonesKathleen M StoesselSarah A WeissMario SznolHarriet M KlugerScott D WalterNiki A SilversteinRenelle Pointdujour-LimPublished in: BMJ open ophthalmology (2022)
Immune checkpoint inhibition can trigger the development of AIR with varied clinical manifestations in patients with advanced cutaneous melanoma. This study highlights the need for close monitoring in cutaneous melanoma patients receiving immunotherapy who develop new visual symptoms with or without funduscopic changes, as well as the potential role for screening of patients prior to initiating immunotherapy.
Keyphrases
- systematic review
- end stage renal disease
- skin cancer
- chronic kidney disease
- ejection fraction
- newly diagnosed
- multiple sclerosis
- optical coherence tomography
- peritoneal dialysis
- emergency department
- prognostic factors
- randomized controlled trial
- diabetic retinopathy
- patient reported outcomes
- depressive symptoms
- risk assessment
- physical activity
- climate change