Design and synthesis of novel 6-substituted quinazoline-2-thiols.
Satya Karuna PulakhandamNaresh Kumar KatariSreekantha Babu JonnalagaddaPublished in: Molecular diversity (2018)
A novel design and efficient protocol for the synthesis of new class of 6-substituted quinazoline-2-thiols is reported. The derivatization of the thioquinazolines is achieved in a strategic manner using 2-aminobenzylamine. The functionalization of the aniline followed by construction of the heterocyclic ring provides a facile way to synthesize these bifunctional quinazolines.
Keyphrases
- molecular docking
- highly efficient
- randomized controlled trial
- ms ms
- liquid chromatography tandem mass spectrometry
- quantum dots
- high performance liquid chromatography
- metal organic framework
- gas chromatography mass spectrometry
- simultaneous determination
- gold nanoparticles
- molecular dynamics simulations
- gas chromatography