Fluid Shear Stress Induces Cell Cycle Arrest in Human Urinary Bladder Transitional Cell Carcinoma Through Bone Morphogenetic Protein Receptor-Smad1/5 Pathway.
Yu-Hsiang LeeChia-Wei LaiYu-Che ChengPublished in: Cellular and molecular bioengineering (2018)
Our findings provided evidences for the effect of mechanical microenvironment on urothelial cancer pathobiology and generated insights into mechanism of LSS-regulated bladder tumor cell cycle.
Keyphrases
- cell cycle
- cell cycle arrest
- cell death
- cell proliferation
- pi k akt
- endothelial cells
- urinary tract
- papillary thyroid
- stem cells
- spinal cord injury
- epithelial mesenchymal transition
- squamous cell
- induced pluripotent stem cells
- transforming growth factor
- transcription factor
- pluripotent stem cells
- signaling pathway
- lymph node metastasis