Effectiveness and safety of low-dose versus standard-dose rivaroxaban and apixaban in patients with atrial fibrillation.
Sylvie PerreaultRobert CôtéAlice DragomirBrian White-GuayAurélie LengletMarc DoraisPublished in: PloS one (2022)
No significant differences were observed in the effectiveness or safety outcome between low-dose and standard-dose rivaroxaban, except for AMI. However, low-dose apixaban was associated with a greater risk of stroke/SE and death without a reduction in the bleeding rates.