MiR-29b regulates Th2 cell differentiation in asthma by targeting inducible B7-H3 and STAT3.

Wenjing GuGang LiWeili ZhangXinxing ZhangYanyu HeLi HuangYongdong YanWei JiChuangli HaoZhengrong Chen

Published in: Clinical and translational allergy (2022)

The expression of miR-29b is decreased in asthmatic children. MiR-29b can inhibit Th2 cell differentiation by inhibiting B7-H3 and STAT3 pathways at the same time, and reduce asthmatic immune inflammation.

Keyphrases

lung function
cell proliferation
chronic obstructive pulmonary disease
poor prognosis
cystic fibrosis
oxidative stress
air pollution
young adults
signaling pathway
allergic rhinitis