A comparative study of tolerability and effects on immunoglobulin levels and CD19 cell counts with ocrelizumab vs low dose of rituximab in multiple sclerosis.
Björn EvertssonTammy HoytAngel ChristensenFaiez Al NimerJohn FoleyFredrik PiehlPublished in: Multiple sclerosis journal - experimental, translational and clinical (2020)
Overall, differences between the two treatments were small. Although the study design precludes robust conclusions regarding the risk-benefit with the studied therapies, our findings indicate that the tolerability and safety with RTX is not inferior to OCR.