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Spinal cord stimulation and rehabilitation in an individual with chronic complete L1 paraplegia due to a conus medullaris injury: motor and functional outcomes at 18 months.

Max O KrucoffRobert GramerDana LottEmily KaleAmol P YadavMuhammad M Abd-El-BarrSaurabh R SinhaShivanand P Lad
Published in: Spinal cord series and cases (2020)
Intraoperatively, no electromyography (EMG) could be elicited with epidural conus stimulation. At 18 months after implantation, his motor ZPPs had advanced from L1 to L5 on the left and from L1 to L3 on the right. Qualitative increases in lower extremity resting state EMG amplitudes were noted, although there was no consistent evidence of voluntary EMG or rhythmic locomotive leg movements. Three validated functional and quality of life (QoL) surveys demonstrated substantial improvements. The modest motor response compared to the literature suggests likely critical differences in the anatomy of such a low injury. However, the change in ZPPs and QoL suggest potential for neuroplasticity even in this patient population.
Keyphrases
  • resting state
  • spinal cord
  • functional connectivity
  • high density
  • systematic review
  • spinal cord injury
  • upper limb
  • neuropathic pain
  • case report
  • cross sectional
  • human health
  • climate change
  • drug induced