Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.
Jennifer R S MeadowsJeffrey M KiddGuo-Dong WangHeidi G ParkerPeter Z SchallMatteo BianchiMatthew J ChristmasKatia BougiouriReuben M BuckleyChristophe HitteAnthony K NguyenChao WangVidhya JagannathanJulia E NiskanenLaurent Alain François FrantzMeharji ArumilliSruthi HundiKerstin Lindblad-TohCatarina GinjaKadek Karang AgustinaCatherine AndréAdam R BoykoBrian W DavisMichaela DrögemüllerXin-Yao FengKonstantinos GkagkavouzisGiorgos IliopoulosAlexander C HarrisMarjo K HytönenDaniela C KalthoffYan-Hu LiuPetros LymberakisNikolaos PoulakakisAna Elisabete PiresFernando RacimoFabian Ramos-AlmodovarPeter SavolainenSemina VenetsaniImke TammenAlexandros TriantafyllidisBridgett M vonHoldtRobert K WayneGreger LarsonFrank W NicholasHannes T LohiTosso LeebYa-Ping ZhangElaine A OstranderPublished in: Genome biology (2023)
We have developed a dense dataset of 1987 sequenced canids that reveals patterns of allele sharing, identifies likely functional variants, informs breed structure, and enables accurate imputation. Dog10K data are publicly available.