Effect of nifedipine and atosiban on perinatal brain injury: secondary analysis of the APOSTEL-III trial.
T A J NijmanM M GoedhartC N NaaktgeborenT R de HaanD C VijlbriefB W MolM J N BendersA FranxM A OudijkPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2018)
In children born before 32 weeks of gestation after the use of tocolytics, the prevalence of brain injury was high. No significant differences were found with respect to overall brain injury between neonates exposed to nifedipine and those exposed to atosiban. However, as this study was a secondary analysis of the APOSTEL III trial, it was underpowered for brain injury. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.