Longitudinal engagement trajectories and risk of death among new ART starters in Zambia: A group-based multi-trajectory analysis.
Aaloke ModyIngrid Eshun-WilsonKombatende SikombeSheree R SchwartzLaura K BeresSandra SimbezaNjekwa MukambaPaul SomweCarolyn Bolton MooreNancy PadianCharles B HolmesIzukanji SikazweElvin Hsing GengPublished in: PLoS medicine (2019)
Among new ART starters in Zambia, we observed 6 patient subgroups that demonstrated distinctive engagement trajectories over time and that were associated with marked differences in the subsequent risk of mortality. Further efforts to develop tailored intervention strategies for different types of engagement behaviors, monitor early engagement to identify higher-risk patients, and better understand the determinants of these heterogeneous behaviors can help improve care delivery and survival in this population.