Efficacy of Poly(ADP-ribose) Polymerase Inhibitors by Individual Genes in Homologous Recombination Repair Gene-Mutated Metastatic Castration-Resistant Prostate Cancer: A US Food and Drug Administration Pooled Analysis.
Jaleh FallahJianjin XuChana WeinstockXin GaoBrian L HeissWilliam F MaguireElaine ChangSundeep AgrawalShenghui TangLaleh Amiri-KordestaniRichard PazdurPaul G KluetzDaniel L SuzmanPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
m should be further explored in future clinical trials.
Keyphrases
- drug administration
- genome wide identification
- dna repair
- clinical trial
- genome wide
- dna damage
- squamous cell carcinoma
- small cell lung cancer
- genome wide analysis
- current status
- copy number
- transcription factor
- dna methylation
- phase ii
- human health
- bioinformatics analysis
- oxidative stress
- randomized controlled trial
- open label
- gene expression
- study protocol
- wild type
- risk assessment