Underweight and obesity are strong predictors of clinical outcomes in patients with ankylosing spondylitis: data from the Smart-phone SpondyloArthritis Management System.
Lidong HuXiaojian JiYiwen WangSiliang ManXingkang LiuLei WangJian ZhuJidong ChengFeng HuangPublished in: Therapeutic advances in musculoskeletal disease (2021)
Both underweight and obesity except for overweight were associated independently with worse disease activity, physical function and health status. Overweight and obesity might impact on treatment responses to biologics in patients with AS. This argues that weight management, to maintain it at a normal level, should be one of the disease management strategies in patients with AS.
Keyphrases
- ankylosing spondylitis
- disease activity
- weight loss
- rheumatoid arthritis
- systemic lupus erythematosus
- weight gain
- rheumatoid arthritis patients
- metabolic syndrome
- insulin resistance
- type diabetes
- physical activity
- body mass index
- juvenile idiopathic arthritis
- high fat diet induced
- adipose tissue
- skeletal muscle
- big data
- artificial intelligence
- deep learning
- replacement therapy