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Low-Dose Image-Guided Pediatric CNS Radiation Therapy: Final Analysis From a Prospective Low-Dose Cone-Beam CT Protocol From a Multinational Pediatrics Consortium.

Sara R AlcornXian Chiong ZhouCasey BojechkoRodrigo A RuboMichael J ChenKarin DieckmannRalph P ErmoianEric C FordDaria KobyzevaShannon M MacDonaldTodd R McNuttAlexey NechesnyukKristina NilssonHakan SjostrandKoren S SmithMarkus StockErik J TryggestadRosangela C VillarBrian A WineyStephanie A Terezakis
Published in: Technology in cancer research & treatment (2020)
A lower-dose cone-beam computed tomography protocol demonstrated table shift vector magnitude that approximate clinical target volume/planning target volume expansions used in central nervous system radiotherapy. There were no significant clinical predictors of setup accuracy identified, supporting use of this lower-dose cone-beam computed tomography protocol across a diverse pediatric population with brain tumors.
Keyphrases
  • cone beam computed tomography
  • low dose
  • radiation therapy
  • randomized controlled trial
  • cone beam
  • high dose
  • early stage
  • computed tomography
  • locally advanced
  • magnetic resonance imaging
  • blood brain barrier