Association Between Fluctuations in Blood Lipid Levels Over Time With Incident Alzheimer Disease and Alzheimer Disease Related Dementias.
Ethan D MoserSheila M ManemannNicholas B LarsonJennifer L St SauverPaul Y TakahashiMichelle M MielkeWalter A RoccaJanet E OlsonVéronique L RogerAlan T RemaleyPaul A DeckerJill M KillianSuzette J BielinskiPublished in: Neurology (2023)
In a large EHR derived cohort, those in the highest quintile of variability for total cholesterol and triglyceride levels had an increased risk of incident AD/ADRD. Further studies to identify the mechanisms behind this association are needed.