Vagus Nerve Stimulation and Seizure Outcomes in Pediatric Refractory Epilepsy: Systematic Review and Meta-Analysis.

Published in: Neurology (2021)

Pooled evidence supports possible effectiveness of VNS in pediatric DRE, although complete seizure freedom is less common. Early referral (fewer trials of ASMs) may be a modifiable factor for desirable seizure outcomes with VNS from a clinical perspective.

Keyphrases

temporal lobe epilepsy
randomized controlled trial
systematic review
primary care
type diabetes
metabolic syndrome
insulin resistance
weight loss
study protocol