Medication Incidents and Medication Errors in Danish Healthcare: a Descriptive Study Based on Medication Incident Reports From the Danish Patient Safety Database, 2014-2018.

In Denmark, reporting of safety incidents to the nationwide Danish Patient Safety Database (DPSD) is mandatory. Medication incident reports constitute the largest category of safety reports. We aimed to provide numbers and characteristics of medication incidents and MEs reported to DPSD focusing on medication, their severity, and the trends therein. This is a cross-sectional study of medication incident reports for individuals ≥18, submitted to DPSD in 2014-2018. We performed analyses on 1) the medication incident - and 2) ME - levels. Out of 479 814 incident reports, 61.18% (n=293 536) were related to individuals ≥ 70, and 44.6% (n=213 974) to nursing homes. Most of the events were harmless (70.87%, n=340 047), and 0.8 % (n=3859) had caused severe harm or death. ME-analysis (n= 444 555) revealed that paracetamol and furosemide were the most frequently reported drugs. The most common drugs for severe and fatal MEs were warfarin, methotrexate, potassium chloride, paracetamol, and morphine. When the reporting ratio for all MEs and harmful MEs was considered, other drugs than the most frequently reported ones were found to be associated with harm. We found a large proportion of harmless medication incident reports and reports from community healthcare services and identified high-risk medicines associated with harm.