The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA).
Frederick S Vom SaalMichael AntoniouScott M BelcherAke BergmanRamji K BhandariLinda S BirnbaumAly CohenTerrence J CollinsBarbara DemeneixAnne Marie FineJodi A FlawsVeronique GayrardWilliam H GoodsonAndrea C GoreJerrold J HeindelPatricia A HuntTaisen IguchiChristopher D KassotisAndreas KortenkampRobin MesnageJane MunckeJohn Peterson MyersAngel NadalRetha R NewboldVasantha PadmanabhanPaola PalanzaZandra PalmaStefano ParmigianiLyn PatrickGail S PrinsCheryl S RosenfeldNiels E SkakkebaekCarlos SonnenscheinAna M SotoShanna H SwanJulia A TaylorPierre-Louis ToutainFrank A von HippelWade V WelshonsDaniel ZalkoR Thomas ZoellerPublished in: Environmental health perspectives (2024)
We strongly endorse EFSA's revised TDI for BPA and support the European Commission's (EC) apparent acceptance of this updated BPA risk assessment. We discuss challenges to current chemical risk assessment assumptions about EDCs that need to be addressed by regulatory agencies to, in our opinion, become truly protective of public health. Addressing these challenges will hopefully result in BPA, and eventually other structurally similar bisphenols (called regrettable substitutions) for which there are known adverse effects, being eliminated from all food-related and many other uses in the EU and elsewhere. https://doi.org/10.1289/EHP13812.