Cognitive consequences of high Aβ amyloid in mild cognitive impairment and healthy older adults: implications for early detection of Alzheimer's disease.
Yen Ying LimKathryn A EllisKarra HarringtonAdrian KamerRobert H PietrzakAshley I BushDavid DarbyRalph N MartinsColin L MastersChristopher C RoweGreg SavageCassandra SzoekeVictor L VillemagneDavid AmesPaul Maruffnull nullPublished in: Neuropsychology (2013)
When compared with HC with low Aβ amyloid, MCI with high Aβ amyloid present with impairments restricted to episodic memory, and the episodic memory impairments in MCI with low Aβ amyloid were accompanied by impairments in executive function, attention, visuoconstruction, and language, suggesting that MCI with high Aβ amyloid reflects prodromal AD, although further longitudinal data is required to confirm this.