Conserved and derived expression patterns and positive selection on dental genes reveal complex evolutionary context of ever-growing rodent molars.

Zachary T CalamariAndrew SongEmily CohenMuspika AkterRishi Das Roy Outi Hallikas Mona M ChristensenPengyang LiPauline MarangoniJukka Jernvall Ophir D Klein

Published in: bioRxiv : the preprint server for biology (2023)

, which plays an important role in mineralizing tissues. Our expression results support conservation of dental genes between voles and model species like mice, while revealing significant effects of overall tooth morphology on gene expression.

Keyphrases

genome wide
gene expression
poor prognosis
dna methylation
oral health
binding protein
bioinformatics analysis
type diabetes
single cell
metabolic syndrome
insulin resistance