Ischemic Colitis Due to Idiopathic Myointimal Hyperplasia of the Mesenteric Veins.
Michael G NoujaimHelen TangKevin KaliszNatasha IranzadDaniel WildPublished in: ACG case reports journal (2023)
Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare and poorly understood noninflammatory ischemic colitis. First reported by Genta and Haggitt in 1991, the disease typically presents with chronic abdominal pain, weight loss, and diarrhea with or without hematochezia in middle-aged men. IMHMV is frequently misdiagnosed as an inflammatory bowel disease. The pathophysiology of IMHMV involves the proliferation of the intimal smooth muscle in mesenteric veins leading to bowel ischemia. The etiology of this process remains unknown. There are no good medical therapies for IMHMV, and surgical resection, a curative intervention, is typically required to make the diagnosis. We present the case of a 66-year-old man with IMHMV diagnosed with endoscopic biopsies.
Keyphrases
- smooth muscle
- middle aged
- abdominal pain
- weight loss
- inferior vena cava
- ulcerative colitis
- ultrasound guided
- randomized controlled trial
- ischemia reperfusion injury
- bariatric surgery
- healthcare
- signaling pathway
- cerebral ischemia
- pulmonary embolism
- type diabetes
- gastric bypass
- insulin resistance
- drug induced
- skeletal muscle
- glycemic control