Prevalence of pre-cluster symptoms in episodic cluster headache: Is it possible to predict an upcoming bout?

Adam Sebastian PedersenAgneta SnoerMads Christian J Barloese Anja Sofie PetersenRigmor Højland Jensen

Published in: Cephalalgia : an international journal of headache (2021)

The majority of episodic cluster headache patients experienced pre-cluster symptoms, and more than half could predict an upcoming bout, suggesting the significant potential of early intervention. Furthermore, the experience of mild cluster headache symptoms and infrequent shadow attacks in remission periods is common and suggest an underlying pathophysiology extending beyond the cluster headache bouts.

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